The Intensive Care Medicine Research Group is part of the department of Cellular and Molecular Medicine at the University of Leuven (Belgium). Our group combines a research laboratory with a large ICU (67 beds, over 2500 patients each year), both located on the Health Sciences Campus of Gasthuisberg. This unique setting allows a very fast and effective interaction among clinicians and basic researchers within the research team, allowing research from  “bed to bench and from bench to bed”. Our overall research objective is to unravel key pathways underlying critical illness-induced organ failure, thereby identifying potential therapeutic targets to enhance recovery. We focus on endocrine and metabolic underlying mechanisms of organ-specific problems evoked by critical illness.